New publication! Lallemand Health Solutions' innovative formula shows significant benefits for occasional stress, sleep quality and skin appearance.
Lallemand Health Solutions is proud to announce the latest results of a proof-of-concept study on Cerebiome®an innovative psychobiotic developed by Institut Rosell® for the microbiome and probiotics. This innovative formula has shown significant benefits for occasional stress, sleep quality and skin appearance.
Cosmebiome: Innovative clinical study
The recently published dermatologist-supervised open-label clinical study investigated the effects of Cerebiome® on 35 healthy Caucasian women, aged 30-45, over an 8-week period. Participants took 3 billion CFU of Cerebiome® once a day.
Significant reduction in perceived stress
The primary outcome measured perceived stress using the PSS-10 scale at the 28e and 56e days. The study revealed a significant reduction in perceived stress, with a decrease of 18 % after 4 weeks and 31 % after 8 weeks. In addition, 79 % of participants reported significant improvements in their mental well-being.
Sleep benefits
Secondary results of the study revealed significant improvements in sleep quality. Participants saw a marked improvement in their ability to fall asleep and stay asleep, as well as a reduction in difficulties staying awake during the day.
Benefits for skin appearance
In terms of skin appearance, Cerebiome® contributed to skin hydration and firmness, reducing the appearance of wrinkles, fine lines and skin tone. A significant increase in skin hydration was noted, with an improvement of 21 % on the face after 8 weeks and up to 18 % on the body. In addition, 85 % of women reported feeling that their skin was more hydrated. The study also showed significant improvements in skin tone, firmness and elasticity, with a 12 % increase in skin firmness after 8 weeks of taking Cerebiome.®. The Cosmebiome study also showed significant improvements in reducing the appearance of fine lines and wrinkles. After just 4 weeks of taking Cerebiome®In the face, participants saw a 7 % reduction in the appearance of facial wrinkles, rising to 17 % after 8 weeks. The forehead area showed even more pronounced results, with a reduction of 12 % after 4 weeks and 21 % after 8 weeks. What's more, 82 % of women reported that their skin was smoother and had an improved texture, demonstrating the powerful impact of Cerebiome® on improving the appearance, texture and overall complexion of the skin.
These results underscore the overall benefits of Cerebiome® for holistic mental well-being and healthy skin
Elodie Aragon, Product Manager at Lallemand Health Solutions, details the potential impact of the study on the nutricosmetics market: " Cerebiome® is already a well-known and easy-to-formulate psychobiotic on the dietary supplement market, with numerous commercial successes worldwide. With this innovative and unique study, we offer our customers the possibility of solutions for the booming nutricosmetics market. This new study enables our customers to make beauty claims with this combination of two probiotic strains".
Applications
The formula is available in a variety of galenic forms, including soluble powders, orodispersible powders, capsules, sachets and more. It can be formulated with ingredients such as riboflavin (vitamin B2) and folic acid (vitamin B9) for skin stress and anti-aging, vitamin B6 for stress/mood and skin balance, melatonin and vitamin B6 for sleep and skin balance, and vitamin C and copper for energy and radiant skin. Cerebiome® and other documented strains can support beauty claims in Europe. From lab to counter, Lallemand Health Solutions has the control and expertise to produce top-quality, tailor-made probiotic formulations in state-of-the-art facilities certified to the highest quality.
Meet the team at in-cosmetics global (stand 1D141) in Amsterdam, Netherlands, April 8-10 to discuss this innovative formula and how you can bring it to your market.
* The formulas claimed are based on scientific data from strains and comply with local regulations.
3. Kassem, O., Tremblay, A., Ghaly, M. S. W., Oula, M.-L., Bronner, S. and Binda, S. (2025). Subjective evaluation of the effects of a probiotic formulation on skin quality in young adult women: Open-label proof-of-concept study. International Journal of Probiotics and Prebiotics, 20(1), 1-9. https://doi.org/10.37290/ijpp2641-7197.20:1-9
Elodie Aragon, Product Manager
Lallemand Health Solutions
[email protected]
lallemand-health-solutions.com/en/
About Cerebiome - A game-changing psychobiotic
Cerebiome® combines two unique strains with complementary effects: Lactobacillus helveticus Rosell®-52 and Bifidobacterium longum Rosell®-175, at a concentration of 3 billion CFU per day, and offering particularly good shelf stability, even at room temperature. A pioneering psychobiotic developed by Institut Rosell® for the Lallemand microbiome and probiotics, which has been involved in research into the mental health applications of probiotics since 1929. It has been extensively researched, including 10 clinical studies on stress and mental well-being, and more than 10 preclinical studies revealing 8 distinct modes of action on the microbiome-gut-brain axis. Notably, Cerebiome® is the only psychobiotic whose health claims have been validated in Canada and Brazil, demonstrating positive impacts on mood, stress and stress-related intestinal discomfort.
About Lallemand Health Solutions
With 90 years of expertise, Lallemand Health Solutions is a world leader in the probiotics industry, specializing in the development, production and marketing of bacterial and yeast-based probiotic supplements for human health.
