in-cosmetics global marks the launch of Solastemis, a new plant-based active ingredient from Gattefossé. With this new ingredient, Gattefossé intends to offer brands, particularly dermocosmetics brands, a powerful active ingredient to protect the skin against UV rays, and respond to the growing needs of consumers concerned with preserving the health of their skin.

A physical barrier between the inside and outside of the body, the skin is one of the most reactive organs to external aggression, particularly UV radiation. By penetrating deep into the DNA of skin cells, UV rays are responsible for structural and functional alterations to the skin's various layers.

A research program focused on the effects of UVA on epidermal stem cells

A few years ago, Gattefossé's skin biology team joined forces with a research group specializing in the study of genotoxic stress in order to understand the effects of UVA radiation on epidermal stem cells.

This collaboration has revealed a greater capacity of epidermal stem cells to fight UVA aggression (compared to their daughter cells), thanks to more efficient repair mechanisms. However, these stem cells remain sensitive to UVA-induced DNA damage and lose part of their self-renewal capacity, known as "stem potential", with long-term consequences for epidermal homeostasis.

Preserve cellular integrity against UVA rays

Gattefossé has developed Solastemis, a natural active ingredient to combat the effects of UVA rays.

This active ingredient acts at the heart of epidermal mechanics, protecting keratinocyte DNA from UVA rays and boosting the skin's natural DNA repair system. It preserves epidermal stem cells, ensuring good homeostasis for the skin's first line of defense.

It also provides a shield for the dermis, protecting key matrix proteins (collagen, elastin) from UVA-induced degradation.

"The primary strength of Solastemis is to offer biological protection against the undesirable effects of UVA on the epidermis. UVA rays are often associated with photoaging, but this is due to their ability to penetrate deeper into the dermis than UVB rays, and to degrade the extracellular matrix, says Boris Vogelgesang, R&D Manager, Cosmetic Active Ingredients. Yet the effects of UVA on the epidermis are undeniable. They contribute significantly to accelerated epidermal aging, notably by affecting the self-renewal capacity of epidermal stem cells, and thus their ability to continuously regenerate the epidermis by producing new cells. By reducing the intracellular oxidative stress caused by UVA irradiation and promoting natural repair mechanisms, Solastemis helps preserve keratinocyte DNA, and consequently their functionality. In addition, the active ingredient has also revealed dermis-preserving properties, offering overall photoprotection of the epidermis and dermis."

A healthier, more radiant complexion and reduced wrinkles

Tested on a panel of 33 Caucasian women aged 37 to 55, in a double-blind active vs. placebo study, Solastemis confirmed its ability to reduce symptoms associated with photoaging.

A significant reduction in crow's feet wrinkles and an overall improvement in skin smoothness and relief are observed. The complexion is beautified, more even, and radiates health.

Sustainable sourcing on Reunion Island

The active molecules in Solastemis are extracted from Sechium edule (also known as chayote or christophine), a fruit grown and harvested by hand according to zero-waste principles, in the heart of the impressive Salazie cirque on the island of La Réunion. Long-term relationships with local growers and harvesters guarantee Gattefossé perfect traceability and quality, from field to laboratory.

As part of its CSR program, Gatt'Up & Act, Gattefossé has undertaken various initiatives to ensure the financial stability and technical development of this sector (supply contract, equipment financing, etc.).

Extraction using NaDES (Natural Deep Eutectic Solvent) technology and a tailor-made manufacturing process (minimum number of steps and limited duration) result in an eco-designed ingredient with high biological performance. The ingredient has a natural origin content of 99.85% according to ISO 16128.

"Today, we're witnessing a real shift, from skin care to more global skin health care. The demand from consumers for health and protection-oriented cosmetics are increasing dramatically. UV protection is a central issue in this health theme, and photo-aging a constant concern. With Solastemis, Gattefossé pushes back the limits of photoprotection. This active ingredient has been developed with the aim of protecting cellular integrity against UVA radiation, by acting at the heart of our cells, at DNA level. This ingredient is the result of several years' research by our experts in natural product sourcing, plant chemistry, cell biology and clinical evaluation. They have combined their know-how to make the most of an exotic fruit, Sechium edule, and transformed it into a powerful active ingredient".says Laurie Canel, Product Marketing Manager - Active Cosmetics.

The 2022 Awards were unveiled yesterday at the in cosmetics show in Paris.

These awards celebrate the latest ingredient innovations that combine pioneering science and product features in a way that demonstrates substantial benefits to manufacturers and end users.

Ingredient companies large and small turned out in droves for this year's awards, with a record 180 entries in four categories: active ingredient, functional ingredient, green ingredient and the Rising Star award. 47 entries were shortlisted, and a panel of industry experts was tasked with selecting the winners, the full list of which is shown below.

Active ingredient

IFF - Lucas Meyer Cosmetics won the gold medal in the Innovation Zone Award for its Wastar Pink Berry. It is designed as an upcycled botanical extract rich in biflavonoids to soothe irritated scalps. By leveraging the pink berry byproducts left over after the extraction of IFF fragrance compounds, Wastar Pink Berry meets the upcycling trend as it combines sustainable sourcing in Madagascar and high efficacy while limiting its manufacturing impact on the environment.

Winning the silver award, DSM Nutritional Products Europe was recognized for its vitamin B12 cryst, while Gattefossé won bronze for its "new DNA guardian", Solastemis.

Functional ingredient

Lubrizol Life Science won gold for its PemuPur Start polymer. A unique, naturally derived polymer emulsifier offering excellent stabilization capabilities at a low level of use while providing a fresh, fast-breaking feel. At the same time, CFF GmbH & Co KG won the silver award for its natural and environmentally friendly raw material Sensocel, and Ashland won the bronze award for its biocellulose natrathix - a biodegradable rheology modifier of natural origin.

Green ingredient

The Green Ingredient Award, in partnership with Ecovia Intelligence, recognizes ingredients that make a proven significant environmental or social difference in the area of sustainability. Nafigate Corporation won the 2022 title for its Biopolymer Hydal PHA - polyhydroxybutyrate, a recycling ingredient and biopolymer. Based on green chemistry and zero waste manufacturing, this new functional ingredient is biocompatible, non-toxic and fully biodegradable. It forms the basis for new formulations as a polymeric matrix.

Also recognized in the green ingredients category, Mibelle Biochemistry won the silver award for its MelanoGray hair greying essence, sustainably obtained by upcycling the pulp of unique organic Chios mandarin peels. Lipoid Kosmetik AG won the bronze award for its PhytoCollagen - an all-natural, Cosmos-certified plant-based alternative to animal collagen with similar cosmetic benefits.

Rising star

The final award of the day, which recognizes first and second year exhibitors, saw Tagra Biotechnologies take home the coveted Rising Star Award. As a world-renowned producer of innovative microencapsulated active compounds, UV filters and pigments, the company's technology results in stable, effective and attractive formulations for cosmetic use. Its innovative microencapsulation technology allows customers to easily develop innovative formulations and products. It was recognized by judges for the range it offers, as well as for its innovation, convenience, number of sectors it can fit into and the solution orientation of its product range.

Sensient Beauty's aim is to provide products and expertise in multi-sensory beauty and personal care applications.

Sensient Technologies' cosmetics subsidiary, Sensient Cosmetic Technologies, suppliers of sensory, functional and active ingredients for the personal care market, has announced a rebranding to Sensient Beauty.

Since 2018, new beauty opportunities responding to new consumer interests have begun to emerge. Naturalness and safety attributes have come to the fore. Demand for hair care products and multi-sensory beauty experiences such as products with innovative textures has increased.

According to Mike Geraghty, President of Sensient Color, "the constant evolution of colors, textures and ingredients in the personal care market is a beautiful thing and fits perfectly with Sensient's strengths and innovation." "We continually assess market and consumer trends to develop products that meet preferences and needs. Opportunities are important."he adds.

Sensient's former brand was primarily focused on the color cosmetics segment of the beauty and personal care market in North America and Europe. It focused primarily on the end-makeup market, especially during the booming cosmetic years from 2013 to 2017, but also maintained an innovation channel for skin and hair care products with a strong impetus on naturalness and sustainability. In the northern Asia-Pacific region, Sensient is a highly regarded supplier of innovative skincare ingredients. Gaelle Frere, Managing Director of Sensient Beauty, states: "Asian skincare routines and textures are still coming to the U.S. and Europe. We decided it was time to deploy the knowledge we gained in Asia-Pacific on a global scale."

Roquette Beauté unveils its new microbiome-friendly ingredient at in-cosmetics Global 2022 in Paris: Beauté by Roquette DE 006 is a 100 % plant-based ingredient, soothing for skin and scalp, which also preserves the diversity of the cutaneous microbiome.

On the occasion of the in-cosmetics Global trade show, taking place in Paris from April 5 to 7, 2022, Roquette Beauté is presenting its new ingredient Beauté By Roquette DE 006, INCI Dextrin, to the cosmetics industry. With Beauté By Roquette DE 006, Roquette Beauté is responding to growing consumer demand for effective, naturally-derived, soothing products for the skin and scalp that preserve the diversity of their cutaneous microbiome.

With an average skin surface area of 2 m², our skin's microbiome is the largest and probably the most diverse. Maintaining its harmony is essential to preserve our skin barrier and avoid skin problems such as inflammation, lack of hydration or sensitive skin.

Every individual has a unique skin microbiota. Many external factors can weaken and influence its balance: temperature variations, UV exposure, pollution, aggressive or synthetic products and lifestyle.

In recent years, consumers have become aware that their skin problems may be associated with an imbalance in the cutaneous microbiota; they now want their skin and scalp care products to combine efficacy and naturalness, while respecting the microbiome.

Beauté by Roquette DE 006: a soothing agent for skin and scalp derived from plants, certified microbiomefriendly.

Beauté by Roquette DE 006 is a Dextrin 100 % of plant origin, Cosmos and Natrue certified and suitable for vegan formulations. According to Roquette Beauté, it's the ideal ally for fragile, sensitive skin and scalps.

Various tests have been carried out to demonstrate the benefits of the ingredient Beauté by Roquette DE 006, according to Roquette Beauté:

• it reduces the marker of inflammation (IL-1 alpha),
• reduces insensible water loss (IWL/TEWL) induced by chemical and mechanical aggression,
• significantly reduces redness induced by chemical aggression, 
• helps soothe the skin and scalp,
• preserves the diversity of skin microflora.

"The addition of Beauté by Roquette DE 006 to our range of ingredients is a perfect illustration of our determination to provide the cosmetics industry with innovative plant-based solutions that meet consumer expectations for safer products with the right balance between naturalness and performance. For us, Sustainable Beauty is all about Skin Health and Nutrition. We focus on the development of high-quality, versatile and sustainable plant-derived ingredients, and develop multifunctional solutions combining high performance and sensoriality".says Bénédicte Courel, General Manager of Roquette Beauté.

Givaudan Active Beauty recently announced the launch of Patchoul'Up, a 100 % upcycled active ingredient capable of rebalancing sebum production, eliminating dry flakes and normalizing the scalp microbiome for overall well-being. Sourced responsibly in Indonesia, Patchoul'Up is made by green fractionation from patchouli leaves distilled after their use as raw material in perfume creation.

"For us, upcycling is not just a trend, but a real path to success on our sustainable business journey. Patchoul'Up supports customer and consumer demand for upcycled solutions that preserve precious natural resources while delivering effective benefits."says Fabrice Lefevre, Active Beauty's Director of Innovation and Marketing.

Hyaluronic acid reinvented

Givaudan Active Beauty also offers an ingredient that acts on fine lines, long-lasting hydration, skin mattification and skin texture: Cristalhyal e-Perfection.

The company says it is reinventing hyaluronic acid (HA) with the launch of this sustainable, patented vectorized complex of bentonite clay and high molecular weight HA (HMW). Engineered by white biotechnology and powered by a modification of the electrostatic charges on the surface of the HA molecule, the triple-action ingredient accesses the skin's deeper layers by electrical attraction to deliver well-aging benefits, long-lasting hydration and mattifying effects.

"Thanks to a proprietary, patented process, bentonite clay can be activated to effectively trap HMW AH molecules in the interstitial space of specific lamellar structures."says Amandine Scandolera, Head of Biological Evaluation for Active Beauty.